Prokaryotic Expression and Purification of Highly Soluble Partial Glycoprotein Erns of Indian Strain of Classical Swine Fever Virus
نویسندگان
چکیده
منابع مشابه
Antibody responses of pigs to defined Erns fragments after infection with classical swine fever virus.
Antibody responses of pigs to defined Erns fragments, after classical swine fever virus (CSFV) infection, were studied by using an enzyme-linked immunosorbent assay (ELISA). Selection of various E(rns) fragments was based on an immunodominant Erns region encompassing three overlapping antigenic regions, amino acids 65 to 145 (Erns(aa)65-145) (AR1), 84 to 160 (Erns(aa)84-160) (AR2), and 109 to 2...
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E2 is one of the three envelope glycoproteins of classical swine fever virus (CSFV). Previous studies indicate that E2 is involved in several functions, including virus attachment and entry to target cells, production of antibodies, induction of protective immune response in swine, and virulence. Here, we have investigated the role of E2 glycosylation of the highly virulent CSFV strain Brescia ...
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By analysing the nucleotide sequence data generated from both the E2 (gp55) and the NS5B genes of classical swine fever virus (CSFV), in addition to previously published data from the 5'NCR, we were able to divide 115 CSFV isolates into two major groups, five subgroups and two disparate isolates. Further discrimination was possible by analysis of sequence data from the E2 region. The three sequ...
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ژورنال
عنوان ژورنال: Indian Journal of Virology
سال: 2012
ISSN: 0970-2822,0974-0120
DOI: 10.1007/s13337-012-0110-3